BDBM50341724 3-amino-6-(2-chlorophenyl)-N-phenylpyrazine-2-carboxamide::CHEMBL1766770

SMILES Nc1ncc(nc1C(=O)Nc1ccccc1)-c1ccccc1Cl

InChI Key InChIKey=GRRRDKOGMLQNSI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50341724   

TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50341724(3-amino-6-(2-chlorophenyl)-N-phenylpyrazine-2-carb...)
Affinity DataIC50:  700nMAssay Description:Inhibition of full length recombinant ATR after 24 hrs by radiometric phosphate incorporation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed